Figure 5 — A new mutation-independent approach to cancer therapy: Inhibiting oncogenic RAS and MYC, by targeting mitochondrial biogenesis

Research Paper|Volume 9, Issue 10|pp. 2098–2116

A new mutation-independent approach to cancer therapy: Inhibiting oncogenic RAS and MYC, by targeting mitochondrial biogenesis

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Figure 5.MYC-RAS-induced mammosphere formation remains sensitive to Doxycycline treatment. Note that mammosphere formation in MCF7-H-Ras (G12V) cells is more resistant to Doxycycline, but this can be overcome by using slightly higher dosages.