Research Paper Volume 9, Issue 7 pp 1825—1843

Aging and calorie restriction regulate the expression of miR-125a-5p and its target genes Stat3, Casp2 and Stard13

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Figure 4. CR reversed age induced upregulation of STAT3 protein expression. Representative western blotting and quantification of STAT3 protein expression in the livers of (A) 5 month old (open bars) or 24 months old (black bars) mice. (B) Mice on AL (open bars) or CR (black bars) mice. * - statistically significant difference (p<0.05). Western blot images displayed in the figure were not subjected to any manipulation.