Research Paper Volume 8, Issue 11 pp 3065—3090

Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation

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Figure 1. Effects of LPS-induced acute inflammation on parameters of contractility of adult (9 mo, n=6 for control and n=6 for LPS-treated groups) and aged (24 mo, n=6 for control and n=6 for LPS-treated groups) mesenteric lymphatic vessels. (A) lymphatic tone index; (B) contraction amplitude; (C) contraction frequency; (D) fractional pump flow. * indicates significant differences (p < 0.05, one-way ANOVA) between control and LPS-treated lymphatic vessels within each age group at any value of transmural pressure. # indicates significant differences (p < 0.05, one-way ANOVA) between adult and aged lymphatic vessels in control group at any value of transmural pressure.