Research Paper Volume 8, Issue 12 pp 3185—3208
Human exceptional longevity: transcriptome from centenarians is distinct from septuagenarians and reveals a role of Bcl-xL in successful aging
Figure 4. Lymphocyte function is preserved in centenarians. (a) Lymphocyte chemotaxis and (b) Natural killer (NK) cell activity assessed in blood samples obtained from young (n=70), septuagenarians (n=70), and centenarians (n=70). (c) Lipid peroxidation marker malondialdehyde (MDA) levels in plasma derived from young subjects (n=31), septuagenarians (n=31), and centenarians (n=27) as determined by HPLC. (d) Protein carbonylation levels in plasma derived from young subjects (n=31), septuagenarians (n=31), and centenarians (n=27) as determined by western blotting. Data are expressed as mean ± SD. *P<0.05; **P<0.01.