Research Paper Volume 8, Issue 11 pp 2747—2753

Figure 3. Biochemical serum profile of ob/ob mice after treatment with PI3K inhibitors. (A) Serum triglycerides (TG) in the same mice as in Figure 1A measured 3-4 hours after the last dosing at the end of the treatment (always under ad libitum feeding). (B) Serum free fatty acids (FFA) as in panel A. (C) Serum lactate as in panel A. Values correspond to average ± s.d. Statistical significance was determined by the two-tailed Student’s t-test relative to vehicle controls: * p< 0.05, ** p <0.01, *** p <0.001.