Research Paper Volume 8, Issue 11 pp 2702—2712

Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer

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Figure 4. ROC curves for predicting disease relapse. In orange disease relapse predicted by Gleason score of the radical prostatectomy alone (AUC = 0.704), green for number of single nucleotide variants (SNVs) in mtDNA alone (AUC = 0.659) and in blue the Gleason score combined with the number of mtDNA SNVs (AUC = 0.752).