Figure 2. Correlation of number of somatic single nucleotide variants (SNVs) with Gleason score. (A) Total number of somatic SNVs per tumor and (B) cumulative variant frequency (CVF) categorized by Gleason score at radical prostatectomy. (C) Total number of somatic SNVs per tumor and (D) CVF categorized by Gleason score of screened biopsy core. P-values represents linear model of SNV predicting pathology score. Diamonds and numbers represent the mean of each group.