Research Paper Volume 6, Issue 7 pp 575—586

Figure 1. Age-related lipid redistribution is decreased in long-lived mice with diminished GH activity. (A) Ratios of extra-/intra-peritoneal (visceral) WAT in 18-month old female Ames dwarf and age-matched non-mutant (NM) littermates. (B) Ratios of extra-/intra-peritoneal WAT in 18-month old female Snell dwarf and age-matched non-mutant (NM) littermates. (C) Ratios of extra-/intra-peritoneal WAT in 18-month old female GHR-/- and age-matched wild-type (WT) littermates. (D) Hepatic triglyceride content in 18-month old female GHR-/- and age-matched wild-type (WT) littermates. Data were analyzed by Student's t-test and are expressed as mean ± SEM of 6 mice per group for A-B, 5 mice per group for C, and 8 mice per group for D. ^*P<0.05; ^$P<0.005.