Research Paper Volume 4, Issue 11 pp 755—767

Beneficial effects of novel antagonists of GHRH in different models of Alzheimer's disease


Figure 5. The effect of MIA-690 on the accumulation of amyloid-β1-42 and τ-protein in the brain of 5XFAD transgenic mice. Mice were treated with daily subcutaneous injections of GHRH antagonist MIA-690 at doses of 2, 5, and 10 μg for 6 months.

* = p − 0.05 vs. control. Data are represented as mean +/− SEM