Figure 1.T-SCE frequencies are significantly elevated upon depletion of tankyrase 1 in telomerase negative backgrounds.T-SCE/chromosome levels were determined in three human fibroblast cell lines with various telomerase statuses; Li-Fraumeni 087 (ALT), 5C-normal human dermal (telomerase negative) and BJ-hTERT (5ta; telomerase positive). (*) is p<0.05.
