Research Paper Volume 2, Issue 10 pp 691—708
Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs
Figure 1. T-SCE frequencies are significantly elevated upon depletion of tankyrase 1 in telomerase negative backgrounds. T-SCE/chromosome levels were determined in three human fibroblast cell lines with various telomerase statuses; Li-Fraumeni 087 (ALT), 5C-normal human dermal (telomerase negative) and BJ-hTERT (5ta; telomerase positive). (*) is p<0.05.