Research Paper Volume 2, Issue 10 pp 650—658

Figure 1. Impaired telomerase activity - Effects on body mass, body composition and energy expenditure. (A) Depicts body mass of 19-24 week old Terc-/- G4 animals (grey) and corresponding controls (black) (n=60 controls, n=61 Terc-/- G4). (B) Relative fat-free mass and (C) relative body fat content in mice as in Panel A (n=60 controls, n=61 Terc-/- G4). (D) Food uptake per individual mouse, depicted for mice as in Panel A (n=30 controls, n=10 Terc-/- G4). (E) Energy excreted via faeces as quantified by direct bomb calorimetry (n=30 controls, n=10 Terc-/- G4). (F) Total energy expenditure normalized to body mass of mice as in Panel A (n=10 controls, n=10 Terc-/- G4).