Klotho interferes with a novel FGF-signalling pathway and insulin/Igf-like signalling to improve longevity and stress resistance in <i>Caenorhabditis elegans</i>

Marie-Thérèse Château; Caroline Araiz; Simon Descamps; Simon Galas

doi:doi:10.18632/aging.100195

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Research Paper Volume 2, Issue 9 pp 567—581

Klotho interferes with a novel FGF-signalling pathway and insulin/Igf-like signalling to improve longevity and stress resistance in Caenorhabditis elegans

Figure 4. Klotho targets daf-2 gene activity and requires a functional daf-2/daf-16 genetic pathway for lifespan modulation. See Figure 2 for legend and Table 2 for corresponding quantitative and statistical analysis.