Research Paper Volume 2, Issue 9 pp 597—611

The ASK1-Signalosome regulates p38 MAPK activity in response to levels of endogenous oxidative stress in the Klotho mouse models of aging

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Figure 6. Western blot analysis of the phosphorylation of the p46- and p54-JNK. The bar graphs and immuno blots show levels of phosphorylation of the catalytic site amino acids, P-Thr183/Tyr185, of p46- and p54-JNK in livers of Klotho (-/-) (129) and WT (129) mice; and (B) in EFmKL 46 Klotho overexpressing and WT mice.