Figure 5.In chronologically aging WT yeast, the life-extending efficacy of LCA under CR exceeds that under non-CR conditions.(A - F)
Effect of various concentrations of LCA on survival (A - D)
and on the fold increase in the mean (E) or
maximum (F) life span of chronologically aging WT strain
cultured in medium initially containing 0.2%, 0.5%, 1% or 2% glucose. Data are presented as means ± SEM (n = 3-28). (G
- I) Effect of 50 μM LCA on the mean or
maximum CLS of WT yeast cultured in
medium initially containing 0.2%, 0.5%, 1% or 2% glucose. Data are presented as means ± SEM (n = 12-28; ***p
< 0.001).
