Research Perspective Volume 2, Issue 7 pp 445—452
SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence
Figure 1. The domain architecture of the different members of the SOCS family of proteins. All eight members of the SOCS family harbor a central SH2 domain and a C-terminal SOCS box. Both SOCS1 and SOCS3 also contain a kinase inhibitory region (KIR). The region of SOCS1 interacting with p53 and ATM are shown [