Research Perspective Volume 2, Issue 6 pp 369—374

Sestrins at the crossroad between stress and aging

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Figure 1. Induction of dSesn after DNA damage. First instar fly larvae were challenged with 4000 rads (R) of gamma radiation, and RNA was extracted after 4 hrs. Northern blot analysis revealed that dSesn mRNA is highly induced upon irradiation. rp49 mRNA was used as a loading control.