Figure 5. Exploratory
activity of wild type and circadian mutant mice. (Upper panel)
Locomotor and rearing activity measured in 5 min increments during 1 hr on
day1 for wt (diamonds), Bmal1-/- (squares), Clock/Clock
(triangles) and Cry1,2-/- (crosses) mice. Statistically significant
difference with wt activity is shown as p values. Difference between wt, Clock/Clock
and Cry1,2-/- locomotor activities, and between rearing activities
of Bmal1-/- vs. Clock/Clock and wt vs. Cry1,2-/- is
not statistically significant. (Lower panel) Cumulative traveled
distance and rearing activity on days 1 and 2; For upper panels p values of
statistically significant differences between wild type and circadian
mutants are indicated. For lower panels * P<0.05.