Research Paper Volume 2, Issue 5 pp 285—297

Circadian clock proteins control adaptation to novel environment and memory formation

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Figure 5. Exploratory activity of wild type and circadian mutant mice. (Upper panel) Locomotor and rearing activity measured in 5 min increments during 1 hr on day1 for wt (diamonds), Bmal1-/- (squares), Clock/Clock (triangles) and Cry1,2-/- (crosses) mice. Statistically significant difference with wt activity is shown as p values. Difference between wt, Clock/Clock and Cry1,2-/- locomotor activities, and between rearing activities of Bmal1-/- vs. Clock/Clock and wt vs. Cry1,2-/- is not statistically significant. (Lower panel) Cumulative traveled distance and rearing activity on days 1 and 2; For upper panels p values of statistically significant differences between wild type and circadian mutants are indicated. For lower panels * P<0.05.