Research Paper Volume 2, Issue 4 pp 200—223

Mitochondrial ROS production correlates with, but does not directly regulate lifespan in drosophila

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Figure 1. Mitochondrial ROS production versus lifespan in three wild type strains of Drosophila melanogaster. (A) Rate of mtROS production (assayed as H2O2, mean + SEM). a, b, c and d indicate statistically significant differences between groups (ANOVA, p < 0.05, n = 5-9 samples per group), m: male, f: female. (B) Survival curves. Combined data from two independent experiments using 100 flies per group per experiment. Mean, maximum lifespans (d) were: DAH males [39,49]; CS males (46, 53); OR males (63, 74); DAH females (79, 84); CS females (69, 81); OR females (86, 91).