Research Paper Volume 2, Issue 3 pp 133—159

Figure 8. Compensatory responses specific for endogenous stressors. (A) Increase in the oxidative stress response do not confer resistance to juglone. Viability was scored as touch-provoked movement after 24 hour recovery from one hour exposure of young adults to juglone. Mean survival (+/- standard error of the mean) relative to untreated control was calculated from five independent experiments comprising a total of 250-350 animals. (B) Lack of nth-1 rescues the lifespan of an xpa-1 mutant. Synchronized L4 larvae were placed on NGM plates at t = 0, incubated at 20°C, and transferred daily to fresh plates during the egg-laying period. The worms were monitored daily for touched-provoked movement; animals that failed to respond were considered dead. The xpa-1 mutant shows a reduced lifespan compared to nth-1 and nth-1;xpa-1 and wild type, N2.