Figure 8.Compensatory responses specific for endogenous stressors.(A) Increase
in the oxidative stress response do not confer resistance to juglone.
Viability was scored as touch-provoked movement after 24 hour recovery from
one hour exposure of young adults to juglone. Mean survival (+/- standard
error of the mean) relative to untreated control was calculated from five
independent experiments comprising a total of 250-350 animals. (B)
Lack of nth-1 rescues the lifespan of an xpa-1 mutant.
Synchronized L4 larvae were placed on NGM plates at t = 0, incubated at 20°C, and transferred daily to fresh
plates during the egg-laying period. The worms were monitored daily for
touched-provoked movement; animals that failed to respond were considered
dead. The xpa-1 mutant shows a reduced lifespan compared to nth-1
and nth-1;xpa-1 and wild type, N2.
