Research Paper Volume 2, Issue 1 pp 28—42
Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration
Figure 7. Effect of rhBMP-4 treatment on secretion of VEGF-A and PEDF from nonpolarized RPE cells. Secretion of VEGF-A (A) and PEDF (C) are presented along with the corresponding cellular VEGF-A (B) and cellular PEDF (D) from three different donors. Data are presented as fold difference as compared to untreated controls. The cellular concentrations of VEGF-A and PEDF did not differ from untreated controls for the entire BMP-4 concentration range.