Research Paper Volume 2, Issue 1 pp 28—42

Attainment of polarity promotes growth factor secretion by retinal pigment epithelial cells: Relevance to age-related macular degeneration

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Figure 4. Distribution of PEDF in apical, central and basal regions in nonpolarized and polarized RPE cells by confocal microscopy. Staining for PEDF is more intense in polarized RPE as compared to nonpolarized RPE. The apical region shows much higher PEDF expression in polarized cells.