Research Paper Volume 2, Issue 1 pp 43—62

Figure 8. mIGF-1 prevents Ang II- and PQ-dependent cell death in HL-1 cardiomyocytes and in mouse neonatal primary cardiomyocytes. (A, B) HL-1 cardiomyocytes were transfected or treated as in Legend of Figure 2A. (C, D) Neonatal primary cardiomyocytes from wild type or mIGF-1 Tg mice were treated as in Legend of Figure 2B. (A-D) Cell viability was monitored with propidium iodide (PI) by flow cytometry and values were normalized to protein content. Results are means ± SE of 3 independent experiments (^*,**,***p versus unstimulated control cells or untreated wild type cardiomyocytes).