Figure 7.mIGF-1 protects the murine heart from PQ-induced oxidative stress. PQ was injected
intraperitoneally at a concentration of 30 mg/kg, while control animals
were injected with a saline solution. All mice were sacrificed 24 hours
after injections. The figure shows representative Western blots of
4-hydroxy-2-nonenal (4-HNE) adduct products (left panel) and of
malondialdehyde (MDA) adduct products (right panel) from wild type,
mIGF-1 Tg, wild type plus PQ and mIGF-1 mice plus PQ. Three animals of a
total of 10 are shown in both panels A and B.
