Figure 4.Induction of ovarian Stra8 expression in adult female mice is correlated with oocyte renewal. (A) Number of non-atretic
immature follicles in ovaries of 2-month-old mice at the indicated times
following a single intraperitoneal injection of DXR (mean ± SEM, n = 4 mice
per group). (B) RT-PCR analysis of Stra8 expression in
contralateral ovaries of 2-month-old mice at the indicated times following
DXR injection (β-actin, house-keeping
gene used as a sample loading control). (C, D) Examples of STRA8-immunopositive
cells (green) in the surface epithelial layer of ovaries of mice 30
hours after DXR injection. Scale bar = 5 μm.
