Priority Research Paper Volume 1, Issue 12 pp 971—978

Aged mouse ovaries possess rare premeiotic germ cells that can generate oocytes following transplantation into a young host environment

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Figure 3. Assessment of the influence of age on the ovarian follicle reserve. (A) Immature follicle numbers in ovaries of young adult (2-month-old) female mice 7 weeks after parabiotic joining with either young adult (3-month-old) or aged (24-month-old) female mice (mean ± SEM, n = 5 mice per group). (B) Immature follicle numbers in young adult (2-month-old) mouse ovaries 3 weeks after grafting under the kidney capsules of young adult (3-month-old), middle-aged (12-month-old) or aged (24-month-old) female mice (mean ± SEM, n = 4 mice per group).