Figure 1. Metaphases of phytohemagglutinin-stimulated peripheral blood lymphocytes. Chromosomes were co-hybridized with peptide nucleic acid (PNA) probes (red) for telomeric sequences and the chromosome 2 centromere serving as internal reference probe, and stained with DAPI (blue). Centromere signals are marked by arrows. (a) Metaphase derived from cord blood of a male newborn, (b) Metaphase from blood of a centenarian male.