Aging
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Figure 8A
Figure 8A.The two mutations, fob1Δ and afo1Δ were combined in a haploid strain from a meiotic tetrad obtained from an isogenic cross. Wild type, the two single mutants and the double mutant were tested for mother cell-specific lifespan. The fob1 mutation does not further increase the lifespan of the afo1 mutant strain (p<0.02).
Figure 8A — The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1 | Aging