Figure 1. Shp-2 reduces endogenous ROS formation.
Endothelial cells were transfected with empty vector (EV), Shp-2 wt or
Shp-2(C459S) and endogenous ROS formation was measured using FACS analysis.
*p<0.05 versus Shp-2 wt. **p<0.05 versus EV. Data are means +/- SEM
(n=6).
The Western blot on the right demonstrates expression of Shp-2 wt and Shp-2(C459S), which were detected with anti-myc antibody.
