Research Paper Volume 1, Issue 5 pp 470—480

Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population

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Figure 2. Haplotype blocks distrubution in the p21 gene generated by Haploview. The two SNPs showing significant differences in frequency between the centenarians and younger controls are bracketed. Every multimarker combination within this block including the two SNPs is significant on the omnibus test for frequency distribution among cases and controls. Table 3 gives the results of the haplotype test.