Figure 3.Effects of RNAi-mediated silencing of survivin and aurora B on S10P histone H3 and SiHa cell phenotype. (A) Survivin, aurora B and S10P
histone H3 protein levels 48h post-transfection. (B) Phase contrast
images of SiHa cells as indicated. (C) Cell cycle distribution at 0,
24, 48 and 72h post-transfection with indicated siRNAs. (D)
Induction of polyploidy in SiHa cells following survivin depletion
indicated by percentage of >G2 cells and appearance of
multinuclear cells.
