Research Paper Volume 16, Issue 8 pp 6652—6672
Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization patients
Figure 4. Models of associations between ApoB, ApoA-1, and the ApoB: A-1 ratio NMR biomarkers and accelerated ages of epigenetic and transcriptomic biomarkers. Models were run with aging predictors (Abbreviations: GA: GrimAge; HaA: Hannum Age; HorA: Horvath Age; PA: Phenotypic Age; TA: Transcriptomic Age) and then adjusted for other aging biomarkers. Models with accelerated ages of epigenetic aging biomarkers were adjusted for GrimAge, Hannum Age, Horvath Age, and Phenotypic Age (GHHP). Models with accelerated ages of transcriptomic and epigenetic biomarkers were adjusted for GrimAge, Hannum Age, Horvath Age, Phenotypic Age, and Transcriptomic Age (GHHPT). Error bars represent a 95% confidence interval. (A–C) show the association between Apolipoprotein B, Apolipoprotein A-1, and the ApolipoproteinB: A-1 ratio and the aging predictors, respectively.