Research Paper Volume 16, Issue 7 pp 6566—6587
Transcranial direct current stimulation promotes angiogenesis and improves neurological function via the OXA-TF-AKT/ERK signaling pathway in traumatic brain injury
Figure 3. The crucial role of OXA in tDCS reduced necrotic neuronal degeneration in in TBI rats. (A) Representative images of Fluoro Jade B (FJB) staining of the injured peripheral cortex in 2W after injury (n = 3). (B) Quantitative analysis reveals the proportion of FJB-positive cells to DAPI (n = 3). (C) Representative images of Tunel staining of the injured peripheral cortex in 2W after injury (n = 3). (D) Quantitative analysis reveals the proportion of Tunel-positive cells to DAPI (n = 3). (E) Representative images of Nissl staining of the injured peripheral cortex in 2W after injury (n = 3). Results are expressed as means ± standard deviation, the statistical significance of differences was evaluated by One-way ANOVA, *denotes the comparison between the Sham group and the TBI group, #represents the comparison between the TBI and the Sham-tDCS group, &signifies the comparison between the tDCS group and the Sham-tDCS group, and ¥indicates the comparison between the tDCS group and the tDCS+SB334867 group. P < 0.05 indicates statistical significance.