Research Paper Volume 16, Issue 8 pp 6731—6744

Electroacupuncture alleviates the symptom of depression in mice by regulating the cGAS-STING-NLRP3 signaling

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Figure 6. The impact of EA and knockdown of cGAS on the production of inflammatory factors and monoamines in depressed mice. (A) The concentration of TNF-α, IL-1β, and IL-6 in the serum was measured by ELISA. (B) The concentration of TNF-α, IL-1β, and IL-6 in the hippocampus was measured by ELISA. (C) The release of 5-HT and NE in the hippocampus was determined by ELISA (*p<0.05 vs control, #p<0.05 vs CUMS).