Research Paper Volume 16, Issue 4 pp 3241—3256
Gut microbiota was highly related to the immune status in chronic obstructive pulmonary disease patients
Figure 8. Construction of IFscore model. (A) Random forest screened out 5 representative IFs with important points. (B) LASSO regression analysis was performed to develop a IFscore model with 5 IFs. (C) The relation of IFscore to the α gut microbiota. (D) The PCA for the β diversity assessment of gut microbiota between high- and low-IFscore samples evidenced that the samples with different IFscore were clustered in different regions. (E) The CCA analysis illustrated IFscore had important influence on the distribution and structure of the gut microbiota. LASSO: least absolute shrinkage and selection operator.