Research Paper Volume 16, Issue 2 pp 1128—1144
An enriched environment ameliorates maternal sleep deprivation-induced cognitive impairment in aged mice by improving mitochondrial function via the Sirt1/PGC-1α pathway
Figure 3. The effect of EE on the increased levels of proinflammation cytokines of aging mice induced by MSD (n = 8). The level of IL-1β in the hippocampus (A) and prefrontal cortex (B). The level of IL-6 in the hippocampus (C) and prefrontal cortex (D). The level of TNF-α in the hippocampus (E) and prefrontal cortex (F). **P < 0.01 vs. males in the control (CON) group; #P < 0.05 and ##P < 0.01 vs. males in the MSD group; $P < 0.05 and $$P < 0.01 vs. females in the CON group; &P < 0.05 and &&P < 0.01 vs. females in the MSD group.