Research Paper Volume 15, Issue 24 pp 15451—15472
Identification and validation of key biomarkers associated with macrophages in nonalcoholic fatty liver disease based on hdWGCNA and machine learning
Figure 2. Single-cell analysis of cell proportion of NAFLD. (A) The features, counts, and percentages of mitochondrial genes in each of the analyzed samples after quality control. (B) The elimination of batch effect. (C) UMAP plot visualizes the distribution of eight cell types in control and NASH mouse livers. (D) Bar plot indicating the cell proportion of all eight cell types in liver of a normal chow diet mice. (E) Bar plot indicating the cell proportion of all eight cell types in liver of NASH mice. (F) Cell fraction distribution differences between NASH and normal. (G) UMAP plot showing the distribution of different clusters of macrophages in livers. (H) Bar plot indicating the proportion of seven macrophage clusters in liver of control and NASH mice. (I) Scatter plot indicating the incoming and outgoing interaction strength of the cells.