Research Paper Volume 16, Issue 1 pp 207—225

Signatures of tumor-associated macrophages correlate with treatment response in ovarian cancer patients

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Figure 9. Knockdown of THEMIS2 in OC cells inhibits cell migration and invasion. (A) THEMIS2 was positively correlated with EMT-related markers. (B) EMT-related pathways were significantly enriched in highly expressed THEMIS2. (C) The expression of EMT-related proteins was significantly affected after THEMIS2 knockout. (D) The invasion ability of OC cells was significantly reduced after THEMIS2 knockdown. (E) The migratory ability of OC cells was significantly reduced after THEMIS2 knockdown.