Research Paper Volume 15, Issue 22 pp 13558—13578

Figure 6. PTCHD4-AS enhanced the sensitivity to CDDP by MSH2-MSH6 dimer in GC cells. (A, B) Viability of SGC7901 and MGC803 cells stably overexpressing EV or PTCHD4-AS after treatment with the indicated concentrations of CDDP for 24 h. (C, D) Cell apoptosis was detected by FACS in SGC7901 and MGC803 cells stably overexpressing EV or PTCHD4-AS after transfection of siRNA for 48h, followed by treatment with CDDP or PBS for 24 h. Data are presented as mean ± SD, * P < 0.05, ** P < 0.01, *** P < 0.001.