Research Paper Volume 15, Issue 24 pp 14915—14929
hsa_circ_0002980 prevents proliferation, migration, invasion, and epithelial-mesenchymal transition of liver cancer cells through microRNA-1303/cell adhesion molecule 2 axis
Figure 6. CADM2 was a target gene of miR-1303. (A) TargetScan analysis was applied to predict the binding site between miR-1303 and CADM2, and the targeting effect of miR-1303 to CADM2 was confirmed using dual luciferase reporter assay. (B) Western blotting analysis of CADM2 expression in HepG2 and Huh7 cells, which were administrated with miR-1303 mimics and circ_0002980 overexpression plasmids. (C) Quantitative analysis of CADM2 protein expression.