Research Paper Volume 15, Issue 23 pp 13799—13821
Integrating scRNA-seq and bulk RNA-seq to characterize infiltrating cells in the colorectal cancer tumor microenvironment and construct molecular risk models
Figure 6. Prognostic model establishment and validation for patients with CRC. (A) Cross-validation for eight OS-related genes in the LASSO regression. (B) Partial likelihood deviance for the LASSO regression for eight candidate genes. (C) The Kaplan-Meier curve was used to analyze the OS of two risk groups of patients with CRC. (D) ROC curves evaluate the predictive ability of the constructed risk model. (E) The results of univariate independent prognostic analysis and multivariate independent prognostic analysis. (F) The nomogram’s calibration curves for predicting 3-, 5-, and 8-year OS in TCGA-CRC cohorts. (G) Based on independent prognostic factors, a nomogram was developed to predict overall survival. The survival rate at 3-, 5-, and 8-year survival rate is predicted according to the total score. (H) The relationship between risk score and common clinicopathological characteristics.