Research Paper Volume 15, Issue 22 pp 13411—13421
Regulatory mechanisms of miR-212-3p on the secretion of inflammatory factors in monocyte-macrophages and the directed differentiation into osteoclasts in ankylosing spondylitis
Figure 5. The directed differentiation of monocyte-macrophages into OCs was induced by 100 ng/mL RANKL added to the medium in each group, and the protein expressions of TRAP, calcitonin, and p-NFATC1 in monocyte-macrophages were measured by Western blotting. OCs, osteoclasts; RANKL, receptor activator of nuclear factor-κB ligand; TRAP, tartrate-resistant acid phosphatase; NFATC1, nuclear factor of activated T cell 1.