Research Paper Volume 15, Issue 22 pp 12966—12981

Figure 5. Effects of hsa-mir-503/hsa-mir-1247 knockdown on migration and invasion ability of 22RV1 cells. (A) The migratory ability of 22RV1 cells was significantly suppressed after hsa-mir-503 knockdown. (B) The invasive ability of 22RV1 cells was significantly suppressed after hsa-mir-503 knockdown. (C) Knockdown of hsa-mir-503 inhibited the lateral migration ability of 22RV1 cells. (D) The migratory ability of 22RV1 cells was significantly increased after hsa-mir-1247 knockdown. (E) The invasive ability of 22RV1 cells was significantly increased after hsa-mir-1247 knockdown. (F) Knockdown of hsa-mir-1247 promoted the lateral migration ability of 22RV1 cells (^*p < 0.05, ^**p < 0.01, ^***p < 0.001 vs. NC inhibitor).