Research Paper Volume 15, Issue 22 pp 12966—12981

Crucial role of hsa-mir-503, hsa-mir-1247, and their validation in prostate cancer

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Figure 1. hsa-mir-503 and hsa-mir-1247 were associated with prognosis of PC. (A) Volcanic map of differential expression of miRNAs. The blue dots were down-regulated miRNAs, and the red dots were up-regulated miRNAs. (B) Univariate analysis of two miRNAs significantly associated with DFS. Abbreviation: HR: hazard ratio. 95% CI: 95% confidence interval. (C, D) KM survival curve. p value was obtained based on log-rank test. (E, F) Violin diagram of differential expression levels of two miRNAs in cancer and para-cancer samples. P value was calculated by Wilcoxon method.