Research Paper Volume 15, Issue 22 pp 12873—12889
Silencing of Dicer enhances dacarbazine resistance in melanoma cells by inhibiting ADSL expression
Figure 2. Clinical relevance of Dicer expression in patients with melanoma. (A) Levels of Dicer expression in melanoma tissues and normal skin tissues, measured using the Oncomine data set. Dicer expression was inversely correlated with (B) primary and metastatic melanoma tissues. (C) Association between Dicer expression and melanoma tumor stages. (D) IHC analysis of the levels of Dicer expression in normal skin tissues and melanoma tissues, (E) IHC analysis of the levels of Dicer expression in tissues sampled during various stages of melanoma. Scale bar: 500 μm. (F) Kaplan–Meier overall survival curves for the levels of Dicer expression in patients with melanoma.