Research Paper Volume 15, Issue 19 pp 10389—10406
Novel diagnostic biomarkers of oxidative stress, immunological characterization and experimental validation in Alzheimer’s disease
Figure 11. The expression value of NFKBIA, PLCE1, CLIC1, SLCO4A1 and TRAF3IP2 in AD animal model. (A) Detection of ROS level in the cortex of mice brain. (B) Detection of MDA level in the cortex of mice brain (n = 5). (C) Detection of GSH level in the cortex of mice brain (n = 5). (D) Detection of OSI level in the cortex of mice brain (n = 5). (E–I) RT-qPCR for NFKBIA, PLCE1, CLIC1, SLCO4A1 and TRAF3IP2 in the cortex of mice brain (n = 5). (J, K) IHC for NFKBIA, PLCE1, CLIC1, SLCO4A1 and TRAF3IP2 in the mice brain. *p < 0.05; **p < 0.01; ***p < 0.001. OSI: Oxidative stress index.