Research Paper Volume 15, Issue 21 pp 11782—11810

Hub gene identification and molecular subtype construction for Helicobacter pylori in gastric cancer via machine learning methods and NMF algorithm

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Figure 3. Selection of the HP-related hub genes via machine learning strategies. (A, B) Boxplot and reverse cumulative distribution curve of residual. (C) Comparison of ROC curves for evaluating the diagnostic reliability of support vector machine-recursive feature elimination (SVM-RFE) and random forest (RF) models. (D) Error graph of RF model. (E) Based on RF algorithm to screen the HP-related hub genes. (F) On the basis of SVM-RFE method to identify the HP-related hub genes.