Research Paper Volume 15, Issue 16 pp 8113—8136
Comprehensive characterization of pyroptosis phenotypes with distinct tumor immune profiles in gastric cancer to aid immunotherapy
Figure 8. The roles of the pyroptosis score in predicting immunotherapeutic responses and chemosensitivity. (A) Interactions of the pyroptosis score with several signaling pathways through Spearman analyses. Red, positive correlation and blue, negative correlation. (B) Distribution of TMB score in high and low pyroptosis score groups in TCGA-STAD cohort. (C–F) Distribution of IPS score of CTLA-4/PD-1 in high and low pyroptosis score groups in TCGA-STAD cohort. (G–J) The estimated IC50- values of cisplatin, docetaxel, gemcitabine, and paclitaxel in patients with high and low pyroptosis scores in the meta-cohort.