Research Paper Volume 15, Issue 16 pp 8044—8060

The alleviating effect and mechanism of GLP-1 on ulcerative colitis

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Figure 3. Effect of GLP-1 on the phosphorylation of AKT/NF-κB p65 and MAPK in DSS-induced colitic mice. The protein levels of p-AKT (A, B), p-NF-κB p65 (A, C), p-ERK1/2 (A, D), p-JNK (A, E) and p-P38 (A, F) were analyzed by western blotting. Data are presented as mean ± SD (n = 6 per group). For GLP-1-DSS vs. DSS group, *p < 0.05 - **p < 0.01 and for DSS vs. NT group, #p < 0.05 were considered significant.