Research Paper Volume 15, Issue 15 pp 7496—7512

Study on the effect of a triple cancer treatment of propolis, thermal cycling-hyperthermia, and low-intensity ultrasound on PANC-1 cells

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Figure 6. The method of triple treatment promoted the inhibitory effect of the heat sensitive chemotherapy drug cisplatin. (A) Cell viabilities of PANC-1 cells and (B) the quantification of PARP cleavage ratio (cleaved PARP/full length PARP) 24 h after the treatment of cisplatin, cisplatin + TC-HT, and the triple treatment of cisplatin + TC-HT + US. Cisplatin concentrations in all treatments were 1 μM. Data were presented as the mean ± standard deviation in triplicate. **P < 0.01, ***P < 0.001, comparison between indicated groups.