Research Paper Volume 15, Issue 15 pp 7440—7450
hsa_circ_0010889 downregulation inhibits malignant glioma progression by modulating the miR-590-5p/SATB1 axis
Figure 3. Downregulation of hsa_circ_0010889 suppressed glioma migration and pulmonary metastasis both in vivo and in vitro. (A, B) Transwell detection showing the migration of both LN229 and U251 cells after transfection with si-hsa_circ_0010889. Data are presented as the mean ± SD. ***P < 0.001 vs. si-NC. (C) Live image detection showing LN229 cell pulmonary metastasis. (D, E) The numbers of metastatic foci in lung tissues were calculated according to the H&E staining. The data are expressed as the mean ± SD. ***p < 0.001 vs. sh-NC.